UpFiber® Beta-Glucan:
Scientifically studied.
Promising for longevity.
Our beta-glucan extract was evaluated in an independent study at Nagi Bioscience, the Swiss biotech pioneer in automated longevity assays, based at EPFL Innovation Park in Lausanne. The study used the world's leading preclinical model for longevity research: Caenorhabditis elegans.
Longevity is one of the fastest-growing areas in nutritional research. The question driving it is simple: can what we eat influence not just how long we live, but how well? Beta-glucan, a natural polysaccharide found in the cell walls of yeast, has attracted growing scientific attention for its potential to support the body's resilience at a cellular level.
Yeastup's beta-glucan is derived from brewer's spent yeast, a byproduct of the brewing process that has been part of human nutrition for centuries. This carefully sourced ingredient combines a long history of safe use with an increasingly compelling body of modern research. Unlike many longevity compounds that remain largely theoretical, ours has now been put to the test in a rigorous, fully automated biological assay designed specifically to measure healthspan.
What the study found
Five concentrations of our yeast beta-glucan were analyzed across the full lifespan of the organisms. The results revealed dose-dependent effects across multiple health parameters:
Biological age
A slowing of the biological aging process was observed across all tested concentrations. At the highest dose, the effect was comparable to caloric restriction, one of the best-evidenced longevity mechanisms known.
Motility
Significantly improved locomotor activity across all concentrations, measured by head and tail amplitude, body bend frequency, and displacement speed.
Reproductive healthspan
Extended reproductive period observed at medium to high concentrations (≥460 µg/ml), indicating a broader effect on overall healthspan duration.
Why C. elegans?
The gold standard of longevity science
This microscopic nematode is the reference model in modern aging research. Around 70% of its genes have human counterparts. Landmark longevity discoveries, including the role of the insulin signaling pathway in aging, were first made in this organism. No other living system enables such precise, fully automated measurement of healthspan, motility, and biological age.
Interested in UpFiber® for your product?
Get in touch with our team to learn more about the study, request the full report, or discuss how UpFiber® beta-glucan fits your application.
Note: This study was conducted in a preclinical model. The results are promising and provide a scientific basis for further research, but do not permit direct claims about effects in humans. Food supplements are not intended for the diagnosis, treatment, or prevention of any disease.
